Search on: COBRA CARDIOTOXIN PROTEINS 
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Descriptor English:   Cobra Cardiotoxin Proteins 
Descriptor Spanish:   Proteínas Cardiotóxicas de Elápidos 
Descriptor Portuguese:   Proteínas Cardiotóxicas de Elapídeos 
Synonyms English:   Cobra Cardiotoxin
Direct Lytic Factors  
Tree Number:   D12.776.831.222
D20.888.850.325.220.222
D23.946.833.850.325.220.222
Definition English:   Most abundant proteins in COBRA venom; basic polypeptides of 57 to 62 amino acids with four disulfide bonds and a molecular weight of less than 7000; causes skeletal and cardiac muscle contraction, interferes with neuromuscular and ganglionic transmission, depolarizes nerve, muscle and blood cell membranes, thus causing hemolysis. 
Indexing Annotation English:   /antag permitted but consider also ANTIVENINS
History Note English:   2008(1978) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DU diagnostic use EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   4239 
Unique Identifier:   D004179 

Occurrence in VHL: 		 

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